Tetsuhiro Tanaka Selected Research

Adiponectin

1/2020	Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice.
1/2019	Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet.

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Tetsuhiro Tanaka Research Topics

Disease

66	Hypoxia (Hypoxemia) 01/2023 - 07/2003
33	Chronic Renal Insufficiency 01/2023 - 05/2006
29	Anemia 11/2022 - 04/2007
10	Fibrosis (Cirrhosis) 01/2023 - 11/2010
8	Inflammation (Inflammations) 09/2022 - 04/2015
7	Neoplasms (Cancer) 12/2023 - 01/2011
6	Diabetic Nephropathies (Diabetic Nephropathy) 01/2023 - 05/2006
6	Kidney Diseases (Kidney Disease) 01/2020 - 01/2012
5	Ischemia 01/2023 - 12/2005
5	Albuminuria 09/2022 - 10/2014
5	Type 2 Diabetes Mellitus (MODY) 01/2021 - 09/2011
5	Reperfusion Injury 01/2020 - 09/2004
5	Proteinuria 01/2020 - 03/2008
4	Body Weight (Weight, Body) 01/2020 - 01/2017
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 06/2006
4	Renal Insufficiency (Renal Failure) 03/2015 - 08/2010
3	Nephritis 04/2015 - 04/2004
3	Hypertension (High Blood Pressure) 01/2015 - 09/2011
3	Heart Failure 01/2015 - 10/2012
2	Adenoma (Adenomas) 04/2024 - 12/2023
2	Hyperaldosteronism (Conn Syndrome) 03/2024 - 12/2023
2	Interstitial Nephritis (Tubulointerstitial Nephritis) 03/2023 - 01/2011
2	Hyperglycemia 01/2021 - 05/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2019 - 01/2019
2	Obesity 01/2019 - 01/2017
2	Chronic Kidney Failure (Chronic Renal Failure) 11/2018 - 01/2012
2	Acute Kidney Injury (Acute Renal Failure) 01/2018 - 01/2017
2	Diabetes Mellitus 05/2017 - 01/2015
2	Glomerulonephritis 04/2015 - 06/2004
2	Uremia 03/2015 - 10/2013
2	Microvascular Rarefaction 12/2014 - 04/2013
2	Edema (Dropsy) 09/2011 - 01/2011
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 10/2023

Drug/Important Bio-Agent (IBA)

19	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2021 - 06/2006
16	Erythropoietin FDA Link 01/2021 - 04/2007
13	Prolyl-Hydroxylase InhibitorsIBA 11/2022 - 01/2009
11	Oxygen (Dioxygen)IBA 09/2020 - 06/2006
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 12/2004
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2009
8	Transcription Factors (Transcription Factor)IBA 09/2020 - 11/2005
7	HematinicsIBA 11/2022 - 08/2013
7	enarodustatIBA 01/2020 - 01/2019
6	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 05/2006
5	EnzymesIBA 03/2024 - 03/2008
5	IronIBA 11/2022 - 01/2015
5	Messenger RNA (mRNA)IBA 01/2019 - 04/2004
5	ElementsIBA 11/2011 - 12/2004
4	ChromatinIBA 01/2023 - 10/2009
4	Histones (Histone)IBA 01/2023 - 01/2011
4	cobaltous chloride (cobalt(II)chloride)IBA 01/2023 - 11/2011
4	CobaltIBA 01/2018 - 07/2003
4	IndicanIBA 03/2015 - 09/2010
4	LuciferasesIBA 11/2011 - 05/2006
3	AldosteroneIBA 04/2024 - 12/2023
3	Advanced Glycation End ProductsIBA 09/2022 - 03/2015
3	Blood Glucose (Blood Sugar)IBA 01/2021 - 04/2015
3	Small Interfering RNA (siRNA)IBA 01/2020 - 08/2015
3	CytokinesIBA 01/2020 - 01/2011
3	Hemoglobins (Hemoglobin)IBA 09/2019 - 01/2015
3	Darbepoetin alfa (Aranesp)FDA Link 02/2019 - 01/2015
3	CollagenIBA 01/2019 - 11/2010
3	RNA (Ribonucleic Acid)IBA 01/2018 - 04/2017
3	Uremic ToxinsIBA 03/2015 - 08/2010
3	pimonidazoleIBA 08/2006 - 05/2004
2	3-deazaneplanocinIBA 01/2023 - 01/2018
2	Long Noncoding RNAIBA 01/2023 - 04/2017
2	Glucagon-Like Peptide-1 Receptor AgonistsIBA 09/2022 - 09/2011
2	CC ChemokinesIBA 09/2022 - 01/2018
2	bardoxolone methylIBA 09/2022 - 01/2021
2	NF-E2-Related Factor 2IBA 01/2021 - 01/2017
2	AdiponectinIBA 01/2020 - 01/2019
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 11/2018
2	Streptozocin (Streptozotocin)FDA Link 01/2020 - 05/2006
2	CreatinineIBA 01/2020 - 01/2018
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 09/2004
2	Cisplatin (Platino)FDA LinkGeneric 10/2019 - 11/2005
2	InterferonsIBA 10/2019 - 04/2004
2	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 05/2017
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 01/2018
2	AST 120IBA 01/2017 - 08/2010
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2017 - 05/2006
2	Dipeptidyl-Peptidase IV InhibitorsIBA 04/2015 - 09/2011
2	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2014 - 09/2011
2	IncretinsIBA 10/2014 - 09/2011
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011 - 10/2005
2	AlbuminsIBA 01/2011 - 03/2008
1	Captopril (Capoten)FDA LinkGeneric 03/2024
1	ReninIBA 03/2024
1	Phospholipases (Phospholipase)IBA 10/2023
1	Toll-Like Receptor 7IBA 10/2023
1	Hexosaminidases (Hexosaminidase)IBA 03/2023
1	Gallium-67IBA 03/2023
1	Biomarkers (Surrogate Marker)IBA 01/2023
1	Growth Differentiation Factor 15IBA 01/2023
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 12/2022
1	Pentoxifylline (Trental)FDA LinkGeneric 09/2022

Therapy/Procedure

17	Therapeutics 01/2021 - 06/2006
1	Catheter Ablation 12/2023
1	Radiofrequency Ablation 12/2023
1	Catheters 12/2023